Individualization of Antihypertensive Drug Treatment

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Individualization of Antihypertensive Drug Treatment

Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation. However, this approach was appropriate decades ago when several drugs had inconveniences that made their use in monotherapy inadvi...

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Trends in antihypertensive drug treatment.

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Cancer death and antihypertensive drug treatment-letter.

The increasing cancer-related mortality related to rapid decreases in blood pressure from the pharmacologic treatment of hypertension as seen in the Systolic Hypertension in the Elderly Program (SHEP; 1) draws interesting parallels to the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) trial (2). The data suggest that some common treatments used for the prevention of cardiovas...

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Cancer death and antihypertensive drug treatment-response.

We wish to thank Drs. Goldstein and Mascitelli (1) for their careful reading of our article (2). In our introduction, we identified prior reports of the association of antihypertensive treatment with cancer and found the results from previous work to be equivocal. We are aware of the findings of PROSPER inwhich new cancer diagnoses were more frequent on pravastatin than on placebo (1.25, 1.04–1...

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Variability in response to antihypertensive drug treatment.

One of the definitions of the word pragmatic is “practical as opposed to idealistic.” Many of the controversies regarding the issue of the use of race to any degree whatsoever in medical decision-making may be more of a result of tensions between pragmatic and idealistic positions on the issue. The biological determinants of human intraarterial pressure are such that there is no precise cutpoin...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2013

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dcs13-2013